Effect of ESRD on Concentration of Serum Creatinine, Urea and Glucose in Male Patients

Authors

  • Abdounasser Albasher Omar Department of Chemistry, Gharyan’s Faculty of Science, Al-jabal Algharbi University, Gharyan, Libya.
  • Rima Rajap Aboud Undergraduate student, Chemistry Department, Gharyan’s Faculty of Science, Al-jabal Algharbi University, Gharyan, Libya.
  • Wijdan Albakoush Undergraduate student, Chemistry Department, Gharyan’s Faculty of Science, Al-jabal Algharbi University, Gharyan, Libya.
  • Rabia Amar Anwesre Chemistry Department, Gharyan’s Faculty of Science, Al-jabal Algharbi University, Gharyan, Libya.

Abstract

There is a limited number of studies about end-stage renal disease (ESRD) in Libya. So, this study was carried out to inspect the effect of ESRD on the concentration of three biochemical parameters in blood serum. Concentrations of serum creatinine (SCr), serum glucose (SGlu) and serum urea (SUr) were measured in 30 males with ESRD and in 30 normal males. SCr and SUr mean values in patient group were found to be higher than the reference interval, and higher than the critical value, too. SGlu mean value was higher than the reference interval, but within the critical interval. Comparison of SCr, SUr and SGlu means, by applying the t-test, revealed significant differences (P < 0.01) between patient group and control group. Some significant relationships (P < 0.05) were found between the study parameters in patient group but not in the control group. Similarly, the significant relationships (P < 0.05) found in control group were not recorded in the patient group. These differences in relationships were accompanied by differences in similarity according to the results of cluster analysis. Briefly, the results reflected the effect of ESRD on SCr, SUr and SGlu concentrations.

 

Author Biographies

Abdounasser Albasher Omar, Department of Chemistry, Gharyan’s Faculty of Science, Al-jabal Algharbi University, Gharyan, Libya.

Msc in analytical chemistry, lecturer at Department of Chemistry, Gharyan’s Faculty of Science, Al-jabal Algharbi University, Gharyan, Libya.

Rabia Amar Anwesre, Chemistry Department, Gharyan’s Faculty of Science, Al-jabal Algharbi University, Gharyan, Libya.

Msc in physical chemistry, lecturer at Department of Chemistry, Gharyan’s Faculty of Science, Al-jabal Algharbi University, Gharyan, Libya.

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Published

2016-08-16

Issue

Vol. 1 (2016)

Section

Articles