Effect of ESRD on Concentration of Serum Creatinine, Urea and Glucose in Male Patients

Abdounasser Albasher Omar, Rima Rajap Aboud, Wijdan Albakoush, Rabia Amar Anwesre

Abstract


There is a limited number of studies about end-stage renal disease (ESRD) in Libya. So, this study was carried out to inspect the effect of ESRD on the concentration of three biochemical parameters in blood serum. Concentrations of serum creatinine (SCr), serum glucose (SGlu) and serum urea (SUr) were measured in 30 males with ESRD and in 30 normal males. SCr and SUr mean values in patient group were found to be higher than the reference interval, and higher than the critical value, too. SGlu mean value was higher than the reference interval, but within the critical interval. Comparison of SCr, SUr and SGlu means, by applying the t-test, revealed significant differences (P < 0.01) between patient group and control group. Some significant relationships (P < 0.05) were found between the study parameters in patient group but not in the control group. Similarly, the significant relationships (P < 0.05) found in control group were not recorded in the patient group. These differences in relationships were accompanied by differences in similarity according to the results of cluster analysis. Briefly, the results reflected the effect of ESRD on SCr, SUr and SGlu concentrations.

 


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References


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MAYFEB Journal of Chemistry and Chemical Engineering

MAYFEB TECHNOLOGY DEVELOPMENT

Toronto, Ontario, Canada

ISSN 2560-693X