QSAR acute aquatic ecotoxicological evaluation of cyclopentanespiro-5-(2,4-dithiohydantoin) towards species of phylum Mollusca

Donyo Ganchev, Marin Marinov

Abstract


QSAR aquatic ecotoxicological evaluation of cyclopentanespiro-5-(2,4-dithiohydantoin) was conducted in order to be revealed the toxicity of tested compound towards animal species from phylum Mollusca with QSAR Toolbox software developed by  Laboratory of Mathematical Chemistry (LMC), Bourgas, Bulgaria. The present paper also makes a comparison between a real trial with Planorbis planorbis (Ram's Horn Snail) and QSAR modelling for determination of the accuracy of the method and modeling algorithms used. This approach - comparison between real tests and QSAR modeling can provide a valuable information about accuracy of the QSAR method and future perfection of it, especially for such non-popular for research studies objects like species from Mollusca phylum.           


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MAYFEB Journal of Agricultural Science
Toronto, Ontario, Canada
MAYFEB TECHNOLOGY DEVELOPMENT
ISSN 2371-512X